You must understand that bipolar disorder is a kind of condition which affects all types of individuals. The children and adults are being affected by such condition. Such is a fact that you must understand. Women would suffer the most from this kind of depression that is called bipolar depression disorder.
This isn’t very strange or far-fetched in any case, since even when the women would suffer from such regular bipolar kind of depression or the depressive disorder, they would often spend more time depressed than they do being manic. Not just women are depressive but the men would also get affected by such kind of condition.
The bipolar kind of disorder is also known as manic depression since such is a mental condition wherein you interchange often between such phases of depression and mania. If you suffer from such bipolar depression, you won’t have to spend a lot of time being manic as you spend getting depressed.
Such kind of depression is a form of disorder and you must understand that it is easy to mistakenly diagnose as bipolar disorder because of the sameness of these symptoms. Because of such, the doctor must keep you around for such a long time when they would try to diagnose the condition you have. It is surely not flattering to either of you when you get treated for a wrong thing.
The bipolar affective disorder is simply another name for such bipolar disorder or the manic-depressive illness. But, you don’t like to mistake this for bipolar depression disorder. Such is closely related with all of the symptoms of such depressive phase of the bipolar disorder, but very few of the mania.
The monotherapy trials from placebo is actually the gold-standard design in knowing the efficacy when it comes to the treatment of bipolar depression. When such efficacy would be proven as monotherapy, the new compounds can be tested in the adjunctive-medication placebo-controlled trials. Those younger adults, without the established need for such long-term medication can be suitable for the clinical trials needing placebo-controls. The switch to mania or such hypomania can be a consequence of the active treatment for such bipolar depression.
Some medications like the tricyclic antidepressants and the venlafaxine can be more likely to prove switch as compared to the others but the increased rate of the switch can’t be seen until about 10 weeks of treatment. Hence, the 12-week trials against placebo are required to determine such risk of switch and to establish such continuing effects. You have to know that such careful assessment at six to eight weeks are needed to guarantee that the patients who fail to respond won’t continue in the study for such unacceptable periods of time.